AUTOLOGOUS DENDRITIC CELL THERAPY IN MESOTHELIOMA PATIENTS ENHANCES FREQUENCIES OF PERIPHERAL CD4 T CELLS EXPRESSING HLA-DR, PD-1, OR ICOS

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS

Introduction: Malignant pleural mesothelioma (MPM) is a malignancy with a very poor prognosis for which new treatment options are urgently needed.We have previously shown that dendritic cell (DC) immunotherapy provides a clinically feasible treatment option.In the current study, we set out to assess the immunological changes induced by DC immunothe

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Identification and Analysis of Wind Shear Within the Transiting Frontal System at Xining International Airport Using Lidar

The principal musta lautanen factor contributing to the restricted accuracy of wind shear detection resides in the rapid oscillations of the wind field and the intricate characteristics of wind shear.The abrupt alterations in wind speed and direction over a short span pose a formidable challenge for conventional detection techniques to precisely ca

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Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells

Objective(s): Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell activecare spitfire lung cancer (NSCLC) exhibit TRAIL-resistance.The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergis

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